• Experimental explorations of general patterns of epistatic interactions in clinical Escherichia coli isolates 

      Pat, Gina (Master thesis; Mastergradsoppgave, 2015-05-13)
      Resistance towards antimicrobial agents is an increasing medical problem nowadays caused by the elimination of susceptible bacteria leaving only the resistant ones to survive and evolve. Evolution through mutations that lead to antibiotic resistance in bacteria increases the diversity of bacterial genomes. Under antibiotic treatment, these mutations might be advantageous for the bacteria, but ...